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These questions have ethical implications owing to

the potential use of the results of individual radiation

sensitivity tests, for example to discriminate between

potential employees.

Whatever the case, there should be no unnecessary

exposure of individuals to ionising radiation, in other

words without justification. Children should receive

particularly close attention in the event of exposure to

ionising radiation for medical purposes.

After the publication in 2014 of the conclusions of the

seminar ASN organised on 16th December 2013, ASN

remains attentive to progress in the knowledge and

international reflections (IRCP in particular) to prepare

for the statutory resolutions that might or will have to

be taken.

1.3.2 Effects of low doses

The Linear No-Threshold (LNT) relationship.

This

hypothesis of this relationship, adopted tomodel the effects

of low doses on health (see point 1.2), albeit practical

from the regulatory standpoint, and albeit conservative

from the health standpoint, is not as scientifically well-

grounded as might be hoped for: there are those who

feel that the effects of low doses could be higher, while

others believe that these doses could have no effect below

a certain threshold, and some people even assert that low

doses have a beneficial effect. Research inmolecular and

cellular biology is progressing, as are epidemiological

surveys of large cohorts. But faced with the complexity

of the DNA repair and mutation phenomena, and the

methodological limitations of epidemiology, uncertainties

remain and the public authorities must exercise caution.

Dose, dose rate and chronic contamination.

The

epidemiological studies performed on individuals exposed

to the Hiroshima and Nagasaki bombings have given

a clearer picture of the effects of radiation on health,

concerning exposure due to external irradiation (external

exposure) received in a few fractions of a second at high

dose and high dose rate. The studies carried out in the

countries most affected by the Chernobyl accident

(Belorussia, Ukraine andRussia) were also able to improve

our understanding of the effects of radiation on health

caused by exposure through internal contamination

(internal exposure) more specifically through radioactive

iodine. Studies on nuclear workers have given a clearer

picture of the risk due to chronic exposure established

over many years, whether as a result of external exposure

or internal contamination.

Hereditary effect.

The appearance of possible hereditary

effects from ionising radiation in humans remains

uncertain. Such effects have not been observed among

the survivors of the Hiroshima andNagasaki bombings.

However, hereditary effects are well documented in

experimental work on animals: mutations induced

by ionising radiation in embryonic germ cells can be

transmitted to descendants. The recessive mutation of

one gene on one chromosome will produce no clinical

or biological indications as long as the same gene carried

by the other counterpart chromosome is not affected.

Although it cannot be absolutely ruled out, the probability

of this type of event nonetheless remains low.

Environmental Protection.

The purpose of radiation

protection is to prevent or mitigate the harmful effects of

ionising radiation on individuals, directly or indirectly,

including in situations of environmental contamination.

Over and beyond environmental protection aiming at the

protection of humans and present or future generations,

the protection of non-human species as such forms part

of the environmental protection prescribed in the French

constitutional Charter for the environment. This subject

has been taken into consideration by the ICRP since 2007

(ICRP 103) and the practical means of dealing with the

protection of nature in the specific interests of animal and

plant species has been the subject of several publications

since 2008 (ICRP 108, 114 and 124).

Blood cell irradiator.

50

CHAPTER 01:

NUCLEAR ACTIVITIES: IONISING RADIATION AND HEALTH AND ENVIRONMENTAL RISKS

ASN report on the state of nuclear safety and radiation protection in France in 2015